RECOMMENDATIONS FOR THE CLASSIFICATION OF GERMLINE VARIANTS IN THE EXONUCLEASE DOMAIN OF POLE AND POLD1

Abstract Background Germline variants affecting the proofreading activity of polymerases epsilon and delta cause a hereditary cancer and adenomatous polyposis syndrome characterized by tumors with a high mutational burden and a specific mutational Car Lighter Power Socket spectrum.In addition to the implementation of multiple pieces of evidence for

A range of alternative media outlets focusing on criticizing immigration politics and mainstream media have Grip Covers emerged in Sweden in recent years.Although they have quite different ideological profiles, they share a clear and critical focus on immigration and mainstream journalistic representations of reality.Their message is that mainstrea